Lou Gehrig’s disease, in brief NYT Crossword Clue

By Emre Parlak /

Crossword Answer

1 ? A
2 ? L
3 ? S
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      Hint 1

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      Think of the initials of a condition associated with a legendary Yankee first baseman.

      Hint 2

      meaning
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      ??? is an abbreviation for Amyotrophic Lateral Sclerosis, a progressive neurodegenerative disease.

      Hint 3

      explanation
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      The clue refers to Amyotrophic Lateral Sclerosis, commonly known as Lou Gehrig's disease, named after the famous baseball player who was diagnosed with it. 'In brief' indicates that the answer is an abbreviation.

      Hint 4

      another clue
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      Green, Gore and more, Hirt and Hirschfeld, Singers Green and Jardine, Gore and more, Lou Gehrig's disease, for short

      Clue Analysis

      The 3-letter answer to “Lou Gehrig’s disease, in brief” in the NYT Crossword May 12 2026 is ALS.

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      Lou Gehrig's disease, in brief Crossword Clue